Pengaruh Paparan Radiasi Telepon Genggam Terhadap Aktivitas Enzim Katalase Kelenjar Parotis Rattus norvegicus Strain Wistar

Authors

  • Yoannita Sarjana Kedokteran Gigi Fakultas Kedokteran Gigi Universitas Hang Tuah
  • Isidora Karsini Penyakit Mulut Fakultas Kedokteran Gigi Universitas Hang Tuah
  • Syamsulina Revianti Biokimia Fakultas Kedokteran Gigi Universitas Hang Tuah

Keywords:

Mobile phone, ROS, Catalase, Oxidative Stress

Abstract

Background: Handheld mobile phones have become a cultural accessory device. Nevertheless, the use mobile phones has given rise to great concern because of possible adverse health effects from exposure to the radiofrequency radiation (RFR) emitted by the device. There have been plenty of researches reportedly establishing the damaging effect of radiofrequency radiation emitted from cell phone on the biological tissues in the body, but only several researches report the effect of handheld mobile phone radiation in oral cavity.
Purpose: The aim of this experiment was to examine the difference effect of rat parotid gland catalase activity cause by low and high radiation handheld mobile phone. Material and Methods: This study was true experimental study with post test only control group design. 72
male Wistar rats, 3 months old, with body weight 200 grams were used in this experiment, devided into 3 major group. Group 1 was negative contol group, group 2 was radiated by handheld mobile phone with low radiation, and group 3 was radiated by handheld mobile phone with high radiation 1 hour per day until 7 days, 14 days, and 21 days. Parotid gland catalase activity was measured by spectrophotometer λ 240. Data were analyzed by Kruskall
Wallis and Mann-Withney test. Result: Low radiation handheld mobile phone was not altered catalase activity until 7, 14 and 21 days. High radiation handheld mobile phone was not altered catalase activity until 7and 14, but catalase activity was significantly increase at 21 days. Conclusion: Radiation emitted from the high radiadion handheld mobile phone until 21days was able to rise rat parotid gland catalase activity .

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References

Anies. Cepat Tua Akibat Radiasi. Pengaruh Radiasi Elektromagnetik Ponsel dan Berbagai Peralatan Elektronik. Elex

Media Komputindo; 2009. Hlm. xiii-xi, 2-1.

Fadhillah. Fenomena Penggunaan HP di Era Informasi bagi Keberadaan Manusia: Suatu Refleksi Filosofis Berdasarkan Pemikiran Heidegger tentang Being and Time. Jurnal Madani 2008; Edisi I: 41-40.

Fall. Cell Phone Radiation Curriculum for Online Course; 2009. Available from http://ilabcentral.org. Diakses 10 Juli 2013.

Adi D. Karakteristik dan Sifat Radiasi Ionizing dan Non Ionizing. Spark Institute; 2014. Available from http://www.academia.edu/5512225/KARAKTERISTIK_DAN_SIFAT_RADIASI_IONIZING_DAN_NON

Gokce S. Effects of Hyperbaric Oxygen during Experimental Tooth Movement. The Angle Orthodontist 2008; 78(2).

Trevor M, Neil S, dan Jennifer K. Electromagnetic Fields From Mobile Phone: Recent Development. Lloyd’s Emerging Risk; 2010. P.13-1.

Procon Organization. Top 10 Highest adn Lowest Radiation Cell Phone. Procon a non profit public charity organization; 2013.

Available from http://cellphones.procon.org/view.resource.php?resourceID=003054. Diakses 10 Juli 2013.

Noor A. Blackberry Gemini Masuk Indonesia. Detik News; 2010. Available from http://inet.detik.com/read/2012/04/24/184101/1900594/317/blackberry-davismasuk-indonesia-gemini-turun-harga.

Hestya R. Samsung Galaxy S4 Terjual 40 Juta Unit; 2013. Available from http://www.tempo.co/read/news/2013/10/ 26/072524865/Samsung-Galaxy-S4Terjual-40-Juta-Unit.

Ferreira A, et al. Ultra High FrequencyElectromagnetic Field Irradiation During Pregnancy Leads to an Increase in

Erytrocytes Micronuclei Incidence in Rat Offspring 2006; 1: 8-1.

Lons S, Ahlbom A, Hall P, dan Feychting M. Mobile Phone Use and Risk of Accoustic Neuromas 2004; 15: 653.

Dirckx JH. Hyperbaric Oxygen Therapy. published by Health Professions Institute; 2009.

Lullis D, Newey RJ, King BV, Aitken RJ. Mobile phone radiation induces reactive oxygen species production and DNA damage in human spermatozoa in vitro. PLos One 2009; 4: 6-4.

Phillips, Singh, Lai. Electromagnetic Fields and DNA Damage.

Pathophysiology Elsevire Journal 2009;16: 88-79.

Mark H. Post Oxidative Stress. Haworth Press; 2000. P. 135-134.

Winarsi H. Antioksidan Alami dan Radikal Bebas. Yogyakarta: Kanisius;2007. Hlm. 100-96.

Frumkin H. Environtmental Health: From Global to Local. Wiley; 2010. P. 16-15.

Piazza. Phone Radiation May EffectnSperm. Vanderbilt University; 2008.mAvailable from http://healthpsych.psy.vanderbilt.edu/2008/Cellphonehealth.htm. Diakses 9 Juli 2013.

Sudibyo. Statistik Penelitian Aplikasi Penelitian di Bidang Kesehatan. Universitas Negeri Surabaya: University Press; 2009. Hlm. 96.

Kusumawati I. Antioxidant and Photoprotective Activity of Quercetin In a Liposome and Free Form. Journal of Chemistry Universitas Diponegoro 2004; 40: 3-2.

Carlos M dan Pablo C. Modulation of Hydrogen Peroxide Production in Cellular Systems By Low Level Magnetic Fields.

Plos One Journal 2011; 3-1.

Nurhayati. Patobiologi Molekuler Kanker. Salemba Medika; 2004. Hlm. 37-36.

Murray K, Granner D, Mayes P, Rodwell V. Harper’s Biochemistry Edisi 25. Jakarta: EGC; 2003. Hlm. 329-321.

Marcey D. 2H2O2 Oxydoreductase.;2011. Available http://www.clunet.edu/BioDev/omm/catalase/cat1.htm. Diakses 10 November 2013.

Koolman J dan Rohm K. Atlas Berwarna dan Teks Biokimia. Hipokrates; 2001.Hlm. 199-198.

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Published

2021-09-14

How to Cite

Yoannita, Isidora Karsini, & Syamsulina Revianti. (2021). Pengaruh Paparan Radiasi Telepon Genggam Terhadap Aktivitas Enzim Katalase Kelenjar Parotis Rattus norvegicus Strain Wistar . DENTA JURNAL KEDOKTERAN GIGI, 10(2), 149–158. Retrieved from https://journal-denta.hangtuah.ac.id/index.php/jurnal/article/view/136

Issue

Vol. 10 No. 2 (2016): Agustus

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Articles

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