The Difference in Blood Pressure Using the Open Extraction Method Before and After Local Anesthesia with Lidocaine + Adrenaline 1:80,000 at RSGM Nala Husada

Authors

  • Mecthildis Vianeys Student of the Faculty of Dentistry, Universitas Hang Tuah, Surabaya, Indonesia
  • Eddy Hermanto Department of Oral Surgery, Faculty of Dentistry, Universitas Hang Tuah, Surabaya, Indonesia

DOI:

https://doi.org/10.30649/denta.v19i1.5

Keywords:

Blood Pressure, Lidocaine Adrenaline 1:80,000, Open Method Extraction

Abstract

Background: Local anesthesia is the first step before open method extraction. The local anesthesia contains 2% lidocaine and adrenaline in a 1:80,000 ratio to extend its duration and reduce the risk of toxicity. However, the use of vasoconstrictors may lead to a spike in blood pressure. Objective: To determine the difference in blood pressure before and after the administration of lidocaine + adrenaline in a 1:80,000 ratio for open method extraction at RSGM Nala Husada Surabaya. Materials and Methods: Blood pressure was measured before and after the administration of local anesthesia containing lidocaine + adrenaline in a 1:80,000 ratio for open method extraction, following the inclusion criteria with a sample size of 21. Blood pressure was measured using an "Omron HEM-FL31" digital sphygmomanometer. Data analysis was performed using a paired t-test. Results: The paired t-test results showed a significant difference in systolic blood pressure (p<0.05), but no significant difference in diastolic blood pressure (p>0.05) before and after the administration of local anesthesia for open method extraction patients. The systolic blood pressure showed the highest value after the administration of local anesthesia (122.95 ± 14.59). Conclusion: Blood pressure showed a significant difference before and after the administration of local anesthesia containing lidocaine + adrenaline in a 1:80,000 ratio for open method extraction at RSGM Nala Husada Surabaya.

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References

Fithri Z, Rochim A, Cholid Z. Distribution of Tooth Extraction Based on Sociodemographic Characteristics of Dental Hospital of University of Jember Pat. e-Jurnal Pustaka Kesehat. 2017 ;5(1):177–84.

Rahman KM, Amir D, Noer M. The Effect of Tooth Extraction on Increasing Blood Pressure in Hypertension Patients. J Health Andalas. 2017;6(1):61.

Barletta M, Reed R. Local Anesthetics: Pharmacology and Special Preparations. Vet Clin North Am - Small Anim Pract [Internet]. 2019;49(6):1109–25. Available from: https://doi.org/10.1016/j.cvsm.2019.07.004

Uchiyama Y, Sumi T, Marutani K, Takaoka H, Murakami S, Kameyama H, et al. Neurofibromatosis Type 1 in the Mandible. Ann Maxillofac Surg. 2018;8(1):121–3.

Tschopp C, Tramèr MR, Schneider A, Zaarour M, Elia N. Benefit and harm of adding epinephrine to a local anesthetic for neuraxial and locoregional anesthesia: A meta-analysis of randomized controlled trials with trial sequential analyses. Anesth Analg. 2018;127(1):228–39.

J H, Andri J, Payana TD, Andrianto MB, Sartika A. Sleep quality is related to changes in blood pressure in the elderly. J Public Asclepius. 2020;2(1):1–11.

Kadir A. Relationship Between Pathophysiology of Hypertension and Renal Hypertension. Ilm Kedokt. 2016;5:15–25.

DANTAS MVM, NESSO B, MITUUTI DS, GABRIELLI MAC. Assessment of patient’s anxiety and expectation associated with hemodynamic changes during surgical procedure under local anesthesia. Rev Odontol da UNESP. 2017;46(5):299–306.

Wijaya MA, Hidayat M, Sitorus TD. Blood Pressure Changes on Tooth Extraction Using Local Anesthesia Contains 1:80,000 Epinephrine at Jatinangor Primary Health Care. J Med Heal. 2018;2(2):706–14.

Al-Hamed FS, Tawfik MAM, Abdelfadil E. Clinical effects of platelet-rich fibrin (PRF) following surgical extraction of lower third molar. Saudi J Dent Res [Internet]. 2017;8(1–2):19–25. Available from: http://dx.doi.org/10.1016/j.sjdr.2016.05.002

Boyanova L. Stress hormone epinephrine (adrenaline) and norepinephrine (noradrenaline) effects on the anaerobic bacteria. Anaerobe [Internet]. 2017;44:13–9. Available from: http://dx.doi.org/10.1016/j.anaerobe.2017.01.003

Abu-Mostafa N, Al-Showaikhat F, Al-Shubbar F, Al-Zawad K, Al-Banawi F. Hemodynamic changes following injection of local anesthetics with different concentrations of epinephrine during simple tooth extraction: A prospective randomized clinical trial. J Clin Exp Dent. 2015;7(4):e471–6.

Manansang GR, Rumampuk JF, Moningka MEW. Comparison of Blood Pressure Before and After Weightlifting. J e-Biomedic. 2018;6(2).

Becker DE, Reed KL. Local anesthetics: review of pharmacological considerations. Anesth Prog. 2012;59(2):90–102.

Komang Krisna Dewi 1*, Lukas Kusparmanto 2 DKPS 3. The Effect of Vasoconstrictor Substances in Local Anesthetic Solutions on Blood Pressure in Tooth Extraction Patients. mderj. 2022;2(1):8–16.

Ramarianda NP. Factors Associated with Blood Pressure in Hypertension Patients. J Health Media. 2018;8(1):63–70.

Craighead DH, Heinbockel TC, Freeberg KA, Rossman MJ, Jackman RA, Jankowski LR, et al. Time-efficient inspiratory muscle strength training lowers blood pressure and improves endothelial function, no bioavailability, and oxidative stress in midlife/older adults with above-normal blood pressure. J Am Heart Assoc. 2021;10(13).

Sari DL, Bahri TS. Strategies for Reducing Stress in Extremity Fracture Preoperative Patients. J Nursing Science. 2017;1–8.

Sihombing TFH, son of KAHP. Organization and Anatomy of the Sympathetic and Parasympathetic Nervous Systems. J Health. 2018;3(4):3–53.

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Published

2025-02-28

How to Cite

Mecthildis Vianeys, & Eddy Hermanto. (2025). The Difference in Blood Pressure Using the Open Extraction Method Before and After Local Anesthesia with Lidocaine + Adrenaline 1:80,000 at RSGM Nala Husada. DENTA JURNAL KEDOKTERAN GIGI, 19(1), 29–35. https://doi.org/10.30649/denta.v19i1.5

Issue

Vol. 19 No. 1 (2025): Februari

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Articles

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