The Effects Of Giving The Lemuru Fish Oil (Sardinella longiceps) Systemically On The Number Of Osteoblasts In Dental Socket Healing Process

Authors

  • Dwi Surya Sudrajat Sarjana Kedokteran Gigi Fakultas Kedokteran Gigi Universitas Hang Tuah
  • Eddy Hermanto Bedah Mulut Fakultas Kedokteran Gigi Universitas Hang Tuah
  • Soemartono*** *Sarjana Kedokteran Gigi Fakultas Kedokteran Gigi Universitas Biologi Oral Fakultas Kedokteran Gigi Universitas Hang Tuah

Keywords:

Lemuru fish, osteoblasts, tooth extraction, socket healing

Abstract

Background: Sockets healing is a dynamic, continuous and overlapping process. Osteoblasts are important cells in healing sockets that will mineralize into bone until the injured tissue heals. Lemuru fish oil (Sardinella longiceps) contains omega 3 which can increase the number of osteoblasts so that it accelerates the process of socket healing after tooth extraction. Purpose: To determine the effect lemuru fish oil that given systemically in increasing the number of osteoblasts in post-extraction tooth socket wound healing. Materials and methods: Experimental research laboratories with post test only control group design. Samples of 33 male Wistar mice were divided randomly into 3 groups. Group K as a control group that was not given lemuru fish oil, group P1 as a group given lemuru fish oil 1.5ml / 200g BB, and P2 group as a group given 1 ml / 200g BB lemuru fish oil. Extraction of left mandibular first incisor was carried out, then extract was given once a day for 7 days with gastric sonde. Observations were made on the 14th day after tooth extraction by calculating the number of osteoblasts in the histology sample using HE (Hematoxylin Eosin). Results: In each treatment group there were significant differences (P <0.05) and significant comparisons (P> 0, 05). Conclusion: Giving lemuru fish oil can increase the number of osteoblasts to post-extraction tooth socket wound healing.

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Published

2021-08-12

How to Cite

Dwi Surya Sudrajat, Eddy Hermanto, & Soemartono*** *Sarjana Kedokteran Gigi Fakultas Kedokteran Gigi Universitas. (2021). The Effects Of Giving The Lemuru Fish Oil (Sardinella longiceps) Systemically On The Number Of Osteoblasts In Dental Socket Healing Process. DENTA JURNAL KEDOKTERAN GIGI, 13(1), 54–60. Retrieved from https://journal-denta.hangtuah.ac.id/index.php/jurnal/article/view/58

Issue

Vol. 13 No. 1 (2019): Februari

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