The Challenges in Treating Uremic Stomatitis Patient with Chronic Renal Failure Disease

Authors

  • Adi Ahmad Yusuf Oral Medicine Specialist Program, Faculty of Dentistry, Universitas Padjadjaran
  • Yanie Febby Martina Lefaan Oral Medicine Specialist Program, Faculty of Dentistry, Universitas Padjadjaran
  • Riani Setiadhi Oral Medicine Departement, Faculty of Dentistry, Universitas Padjadjaran

DOI:

https://doi.org/10.30649/denta.v16i2.7

Keywords:

Chronic Renal Failure, Challenges, Uremic Stomatitis

Abstract

Background: Uremic stomatitis is a rare oral manifestation of chronic and acute kidney disease. The incidence of uremic stomatitis is low, especially because process disease develops gradually over years and occurs in advanced renal failure. This disease is associated with high levels of blood urea. There are four forms of uremic stomatitis that have been identified, namely ulcerative, erythemopultaceous, hyperkeratotic and hemorrhagic. Usually the lesions were seen on buccal mucosa, dorsal or ventral surface of tongue, gingiva, lips and floor of mouth. Purpose: To discuss the challenges in treating uremic stomatitis patient with poor systemic condition. Case: A 73 year old male patient was referred from cardiology department to oral medicine department because there were painful lesions on lips, tongue, palate and buccal mucosa. He was a chronic kidney disease patient whose laboratory results showed high urea and creatinine values. Case management: The Patient was given oral hygiene instruction to clean his teeth and tongue with a gauze soaked in NaCl at least three times a day, compressing the lips and rinse with chlorine dioxide based mouthwash (Oxyfresh®, USA) three times a day. The improvement of oral lesions were not significant because the blood urea and creatinine value were still high. Conclusion: Management of uremic stomatitis needs multidisciplinary teamwork in order to achieve the kidney function and other comorbidities improvement as well as oral lesions to improve the quality of life.

 

Downloads

Download data is not yet available.

References

Antoniades DZ, Markopoulos AK, Andreadis D, Balaskas I, Patrikalou E, Grekas D. Ulcerative Uremic Stomatitis Associated with Untreated Chronic Renal Failure: Report of a Case and Review of The Literature. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology. 2006; 101(5): 608–13.

Sudarshan R, Annigeri R, Mamatha G, Vijayabala Gs. Uremic stomatitis. Contemp Clin Dent. 2012; 3(1):113.

Talish M, DiLorenzo AM. Uremic Stomatitis. New England Journal of Medicine. 2020; 382(26): 2556.

Romagnani P, Remuzzi G, Glassock R, Levin A, Jager KJ, Tonelli M, et al. Chronic Kidney Disease. Nat Rev Dis Primers. 2017;3.

Rangaswami J, Bhalla V, Blair JEA, Chang TI, Costa S, Lentine KL, et al. Cardiorenal Syndrome: Classification, Pathophysiology, Diagnosis, and Treatment Strategies: A Scientific Statement From the American Heart Association. Circulation. 2019 Apr 16; 139(16): E840–78.

Ronco C, Bellasi A, Di Lullo L. Cardiorenal Syndrome: An Overview. Adv Chronic Kidney Dis. 2018 Sep; 25(5): 382-390. doi: 10.1053/j.ackd.2018.08.004. PMID: 30309455.

O’connor NR, Corcoran AM. End-Stage Renal Disease: Symptom Management and Advance Care Planning [Internet]. AAFP Lifestyle Medicine. Vol. 85. 2012. Available from: www.aafp.org/afp.

Bachani L, L. A, Singh M, Kumar S, Tiwari T. Ulcerative Uremic Stomatitis: Canary in a Coalmine. Saudi Journal of Medicine. 2019; 04(09): 682–6.

Liao CY, Wu CC, Chu PL. Uremic stomatitis. Qjm. 2017;110(4):247–8.

Klein M, Munerato MC. Uremic Stomatitis in Three Patients and Review of The Literature. JSM Dent. 2016; 4(4):1–4.

Oyetola EO, Owotade FJ, Agbelusi GA, Fatusi OA, Sanusi AA. Oral Findings In Chronic Kidney Disease: Implications for Management in Developing Countries. BMC Oral Health. 2015; 15(1):1–8.

Dioguardi M, Caloro GA, Troiano G, Giannatempo G, Laino L, Petruzzi M, et al. Oral Manifestations in Chronic Uremia Patients. Ren Fail. 2016; 38(1):1–6.

Mini M, Prasad TS, Thomas V. Uremic Stomatitis: Report of Two Cases. Oral and Maxillofacial Pathology Journal. 2015; 6(2):636–8.

Yano H, Kinjo M. Uraemic Stomatitis. BMJ Case Rep. 2019; 12(10):1–2.

He L, Wei Q, Liu J, Yi M, Liu Y, Liu H, et al. AKI on CKD : Heightened Injury, Suppressed Repair, and The Underlying Mechanisms. Kidney Int. 2017; 92(5):1071–83.

Murugan R, Kellum JA. Acute kidney injury: what's the prognosis? Nat Rev Nephrol. 2011 Apr; 7(4): 209-17. doi: 10.1038/nrneph.2011.13. Epub 2011 Feb 22. PMID: 21343898; PMCID: PMC3547642.

Farida LS, Thaha M, Susanti D. Characteristics of Patients with End-Stage Renal Disease at Dialysis Unit Dr. Soetomo General Hospital Surabaya. Biomolecular and Health Science Journal. 2018; 1(2): 97.

Saini R. A Prospective Experimental Comparative Study On The Clinical and Antimicrobial Effects of Chlorine Dioxide Based Toothpaste and Mouthrinse in Periodontitis Patients- A One Year Follow-Up Study. International Journal of Biomedical and Advance Research. 2015; 6(605): 149–53.

Arunkumar S, Annigeri RG, Shakunthala GK. Ulcerative Uremic Stomatitis - Review of The Literature and A Rare Case Report. Journal of Krishna Institute of Medical Sciences University. 2015; 4(1): 148–54.

Huang BS, Wu SC, Lin CY, Fan KH, Chang JTC, Chen SC. The Effectiveness of A Saline Mouth Rinse Regimen and Education Programme on Radiation-Induced Oral Mucositis and Quality of Life In Oral Cavity Cancer Patients: A Randomised Controlled Trial. Eur J Cancer Care (Engl). 2018; 27(2): 1–10.

Downloads

Published

2022-08-31

How to Cite

Adi Ahmad Yusuf, Yanie Febby Martina Lefaan, & Riani Setiadhi. (2022). The Challenges in Treating Uremic Stomatitis Patient with Chronic Renal Failure Disease. DENTA JURNAL KEDOKTERAN GIGI, 16(2), 103–108. https://doi.org/10.30649/denta.v16i2.7

Issue

Section

Articles