Karakterisasi Esktrak Air Teripang Emas (Stichopus hermanii)

Authors

  • Dian Widya Damaiyanti Biologi Oral Kedokteran Gigi Universitas Hang Tuah

Keywords:

Gold sea cucumber, active substance, water extract, wound healing

Abstract

Background: Indonesia is the country with the biggest sea cucumbers world’s producer. So far, sea cucumbers are only used as a side dish alone. Indonesia can provided added value and high economic value of gold sea cucumber through right procedure. A lot of gold sea cucumbers active substance that are suspected to have an influence on wound healing. For the best result, extract gold sea cucumber must be prepare with correct procedure. Water extract is one of a safe procedure with a small risk that may damage parts of the active substance. Purpose: The aim of this study is to know the characterization of water extract gold sea cucumber (Stichopus hermanii). Materials and Methods: Gold sea cucumbers were collected, homogenized with distillated water and shaken with water-bath shaker. Then extract was freeze dried, the result then characterized using spectrophotometer. Result: The
largest component to fewest component of water extract gold sea cucumber is total protein 76,82%, essential amino acid 48,11%, non essential amino acid 28,70%, glycoprotein 4,62%, collagen 4,05%, GAG’s 1,62%, proteoglycan 1,13%, heparin sulfat 1,02%, calcium 59%, saponin 56%,heparin 38%, hyaluronat acid 29%, calcium 0,59%, Zinc 0,01%. Conclusion: There is many active substance of water extract gold sea cucumber that involed in wound healing process.

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References

Tehranifard Akram, Shahrbanoo Oryan Gholamhossin Vosoghi. 2011. Introducing a Holothorian sea cucumber species Stichopus

hermanni form Kish island in the Persian Gulf in IRAN . International Conference on Environment and Industrial Innovation IPCBEE vol. 12.

IACSIT Press, Singapore. P. 143-138.

Arylza. Irma Shita. 2009, Teripang dan Bahan Aktifnya, Oseana. 34(1): 16-9.

Ridzwan B.H., Zarina M.Z, Kaswandi M A, Nadirah M and Shamsuddin A.F. 2001. The Antinociceptive Effects of Extracts from Stichopus

chloronotus Brandt. Pakistan Journal of Biological Sciences, 4 (3): 246-244.

Yulianto, Putri E. Pengaruh Ekstrak Gamat (Stichopus hermanii) Terhadap Proliferasi Sel Fibroblas Pada Proses Penyembuhan Luka Tikus

Wistar (Penelitian Pendahuluan). Skripsi. FKG. Universitas Airlangga.

Masre S, Kip George W, Sirajudeen K N, Ghazali F. 2010. Wound Healing Activity of Total Sulfated Glycosaminoglycan (GAG) From Stichopus Vastus and Stichopus Hermanii integumental Tissue in Rats. International Journal OF Molecular Medicine and Advance Science 6 (4): 53-49.

Septiana, A. T., & Asnani, A. 2012. Kajian sifat fisikokimia ekstrak rumput laut coklat (Sargassum duplicatum) menggunakan berbagai pelarut dan metode ekstraksi. Jurnal Argointek, 6(1): 28-22.

Riyanto, B., Nurhayati, T., & Pujiastuti,A. D. 2013. Karakterisasi Glikosaminoglikan Dari Tulang Rawan Ikan Pari Air Laut (Neotrygon Kuhlii)

Dan Pari Air Tawar (Himantura Signifer) Characterisation Of Glycosaminoglycan From Marine Skate (Neotrgon Kuhlii) And Freshwater Skate (Himantura Signifer) Cartilage, JPHPI, 16(3): 231224.

AnnaR,Suhandar,Jakaria, dan Suharmadi, 2013, Uji Fungsi Freeze Dryer Radiofarmaka, Seminar Prosiding Penelitian Dan Pengelolaan Perangkat Nuklir PusatTeknologi Akselerator dan Proses Bahan Yogyakarta, Rabu,11September.

Yılmaz1 Nergiz , Nisbet Ozlem, Nisbet Cevat, Ceylan Gozlem , Hoşgor Fatih, Dede O.Doğu. 2009. Biochemical Evaluation Of The Therapeutic

Effectiveness Of Honey In Oral Mucosal Ulcers. Bosnian Journal Of Basic Medical Sciences, 9(4): 295-290.

Dharma Budi, Prihartiningsih, dan Rahardjo. 2010. Pengaruh Suplemen Zink Soket Gigi Marmut yang Mengalami Defensiensi Zink pasca Pencabutan Gigi., jurnal kedokteran gigi, 1(3): 98-94,UGM.

Miller Gregory D., PhD, and John J.B.Anderson, PhD. 1999. The Role of Calcium In Prevention of Chronic Diseases. Journal of the American

College of Nutrition,18(5), 372S–371S.

Sirko S, Holst Alexander von , Weber Anika, Wizenmann Andrea, TheocharidisUrsula, Götz Magdalena, Faissner Andreas. 2010. Chondroitin sulfates are required for fibroblast growth factor-2dependent proliferation and maintenance in neural stem cells and for epidermal growth factor-dependent migration of their progeny. Stem Cells. Pub med, 28(4): 775-87.

Kumar, V., Abbas, A.K., and Fausto, N. 2010. Robbins and Contran: Pathologic Basis of Disease. 8th Edition. Philadephia: Elsevier Saunders Inc.,10591.

Puryanto. Kelik. 2009. Uji aktivitas gel ekstrak etanol daun Binahong (anredera cordifolia (tenore) steen.) Sebagai Penyembuh luka bakar

pada kulitPunggung kelinci. Skripsi. Universitas Muhammadiyah Surakarta.

Watkins, BA, Li Y, Lippman HE, Seifert MF. 2001. Omega-3 polyunsaturated fatty acids and skeletal health, Exp Biol Med (Maywood), 226: 497-485.

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Published

2021-12-01

How to Cite

Dian Widya Damaiyanti. (2021). Karakterisasi Esktrak Air Teripang Emas (Stichopus hermanii) . DENTA JURNAL KEDOKTERAN GIGI, 9(1), 74–81. Retrieved from https://journal-denta.hangtuah.ac.id/index.php/jurnal/article/view/209

Issue

Vol. 9 No. 1 (2015): Februari

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